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KMID : 0854720060260030254
Korean Journal of Asthma, Allergy and Clinical Immunology
2006 Volume.26 No. 3 p.254 ~ p.258
Two Cases of Serum Sickness Reaction Induced by Bee Stings
Bae In-Gyu

Jeong Yong-Geun
Ma Jeong-Eun
Lee Seung-Jun
Kim Hyun-Ok
Kim Dong-Wook
Park Jin-Yong
Cho Yu-Ji
Park Dong-Jun
Jeong Yi-Yeong
Abstract
The usual reactions after an insect sting are mild redness and swelling at the stinging site, and the most serious reaction is anaphylaxis. There have been isolated reports of late-onset reactions, such as vasculitis, nephritis, neuritis, and serum sickness, occuring in association with an insect sting. Late-onset reactions, including serum sickness, occur much less frequently. We report 2 individuals who developed serum sickness reaction after bee stings. A 35-year-old male, a family member of beekeeper, had stung frequently. About 10 days after bee stings, he complained of fever, migratory polyarthralgia, erythematous skin rash, and myalgia. High levels of specific IgE to bee venom were detected by the radioallergosorbent test (RAST). The other patient was a 25-year-old male who presented with urticaria, angioedema, arthralgia, myalgia, fever, and skin rash about 7 days after a bee sting. He also had high titers of specific IgE to bee venom. We here report two cases of serum sickness reaction caused by bee stings.
KEYWORD
Serum Sickness, Bee venom, Specific IgE, Insect sting
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